Request for Funding

Medical Student Research Fellowship for Summer 2001

Mentor: Skip Garner

Department: Biochemistry / Internal Medicine

Room number: NA2.508

Mail Code: MC 8591

Phone number: 214-648-1661

E-mail: Garner@swmed.edu

Human subjects IRB approved project number (where applicable): N/A

Animal subjects IRB approved project number (where applicable): N/A

Project Type:

(patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

Basic research

Three Projects

Brief Description of Project 1:

Project title: Applications or digital light processing (DLP) to Biomedicine

Mentors: Skip Garner / Alex Pertsemlidis

Biomedical researchers report their findings in scientific literature, 400,000 papers per year. Students will work in our group to develop software to extract information from text and identify hidden correlations and knowledge. We wish to build a system for all UTSW faculty to access. Software will be written using our PC workstations, HP parallel computers, a 32 CPU Linux cluster and a 1.3TB RAID storage system.

Brief Description of Project 2:

Project title: Applications or digital light processing (DLP) to Biomedicine

Mentors: Skip Garner / Kevin Leubke

We have developed a technology to manufacture DNA oligonucleotide chips with ~200,000 analyses per chip. This enables many new research projects. We wish to analyze tumors and cell lines for lesions in the coding and regulatory regions of 1,000's of genes implicated in cancer. Students will work on one assay, from sample preparation to data interpretation.

Brief Description of Project 3:

Project title: Applications or digital light processing (DLP) to Biomedicine

Mentors: Skip Garner / Michael Huesbschman

We have developed technologies for the intensity and phase control of light. Applications include microscopy, custom light sources and image projection. A medical student with a physics or engineering background who wishes to work on a scientific demonstration of an application of TI's DLP chips in our lab. Students will use DLP chips with 800,000 micro mirrors, lasers, optics and CCD cameras.

Previous Research Activities or Publications with Medical Students:

Over the past several years a number of successful research projects have been computed. Several publications have come from this work.

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