Request for Funding

Medical Student Research Fellowship for Summer 2002

Mentor: Yi Liu
Department: Physiology
Room number: L4.235
Mail Code: MC9040
Phone number: 214-648-3701
E-mail: yi.liu@UTsouthwestern.edu
Project title: Molecular mechanism of circadian clocks

Human subjects IRB approved project number (where applicable):

Animal subjects IRB approved project number (where applicable):

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)
Basic Research

Brief Description of Project:

Circadian clocks have been described in almost all organisms ranging in complexity from single cells to mammals and function to control daily rhythms in a variety of biochemical, cellular, physiological and behavioral events. These rhythms have a period close to 24 hours (circadian) and persist in the absence of external time cues.
Our lab is using filamentous fungus Neurospora crassa, one of the best studied model organisms for circadian clocks, to understand the molecular mechanisms of
eukaryotic circadian clocks. Projects in the lab will include using molecular, biochemical and physiological approaches to study the functions of several known clock genes.

Previous Research Activities or Publications with Medical Students:

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