Medical Student Research Fellowship for Summer 2005

Mentor: Robert Toto
Department: Internal Medicine
Room number: H5.122
Mail Code: 8856
Phone number: 83442
E-mail: groupwise
Project title: Improving Outcomes in Diabetic Nephropathy

Human subjects IRB approved project number (where applicable): 0202-065

Animal subjects IRB approved project number (where applicable):

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

Patient Based

Brief Description of Project:
This is a randomized double blind placebo controlled trial to determine efficacy and safety of add on therapy with either an angiotensin II receptor blocker or a mineralocorticoid antagonist to maximally dosed ACE inhibitor therapy in patients with established diabetic nephropathy and persistent proteinuria. The project involves direct patient contact and has a GCRC component in which renal function and endocrine measurements of renin-angiotensin system are performed under controlled conditions repeatedly over a year long protocol.

Previous Research Activities or Publications with Medical Students:
I have very limited experience with research activities involving medical students and no publications with them.

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