Medical Student Research Fellowship for Summer 2006

Mentor: Dr. Mark Drazner
Department: Cardiology/Internal Medicine
Room number:
Mail Code: 9047
Phone number: 214-645-7515
E-mail: Mark.Drazner@UTSouthwestern.edu
Project title: Renal Function and LV Mass and Function: The Dallas Heart Study

Human subjects IRB approved project number (where applicable): 112004-015

Animal subjects IRB approved project number (where applicable):

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects) Patient based

Brief Description of Project:

Using the Dallas Heart Study as a platform, we will examine the basis of inter-individual differences in LV structure and function with a focus on the impact of renal disease including microalbuminuria. Multivariable models will be constructed to assess the independent contribution of renal abnormalities on changes in LV mass and LVEF, stratified by ethnicity.

Previous Research Activities or Publications with Medical Students:
1. King, LP, Siminoff, LA, Meyer, DM, Yancy, CW, Ring, WS, Mayo, TW, Drazner, MH. Health insurance and cardiac transplantation: a call for reform. J Am Coll Cardiol 45:1388-1391, 2005.
2. Chung, AK, Das, SR, Leonard, D, Peshock, RP, Kazi, F, Abdullah, SM, Canham, RM, Levine, B, Drazner, MH. Women have a higher left ejection fraction than men independent of their smaller left ventricular volume: the Dallas Heart Study. Circulation, 113: 1597-1604, 2006.

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