Medical Student Research Fellowship for Summer 2006

Mentor: Jay D. Horton
Department: Internal Medicine/Molecular Genetics
Room number: L5.230
Mail Code: 9046
Phone number: 8-9677
E-mail: jay.horton@utsouthwestern.edu
Project title: Characterization of the interaction of PCSK9 with the LDL receptor

Human subjects IRB approved project number (where applicable):

Animal subjects IRB approved project number (where applicable):

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects) Basic Research.

Brief Description of Project:
PCSK9 regulates the protein levels of the LDL receptor through as yet undefined mechanisms. Preliminary studies suggest that PCSK9 directly binds to the LDL receptor. This project will entail further defining the details of this interaction.

Previous Research Activities or Publications with Medical Students:

None

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