Medical Student Research Fellowship for Summer 2007

Mentor: Jinming Gao
Department: Simmons Comprehensive Cancer Center
Room number: Y4.306
Mail Code: 8807
Phone number: 214-648-9278
E-mail: jinming.gao@utsouthwestern.edu
Project title: Micellar Nanomedicine for cancer-targeted imaging and therapy

Human subjects IRB approved project number (where applicable): N/A

Animal subjects IRB approved project number (where applicable): APN 1073-06-02-1

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

Animal-based research

Brief Description of Project:

Evaluation of the cancer specificity and imaging efficacy of cRGD-encoded polymeric micelles (self-assembled nanoparticles) in tumor-bearing mice by MRI. Histological validation of the imaging efficacy by histochemistry.

More details on:
http://www4.utsouthwestern.edu/gaolab/index.html

Previous Research Activities or Publications with Medical Students:

Brent Weinberg is an MD/PhD student in the lab who is expecting to receive his PhD this year. The following is a few first authored papers that Brent has published:

(1) Weinberg, B.; Ai, H.; Blanco, E.; Anderson, J.M.; Gao, J. Antitumor Efficacy and Local Pharmacokinetics of Doxorubicin via Intratumoral Delivery from Polymer Millirods. J. Biomed. Mat. Res. 2007, 81, 161-170.
(2) Weinberg, B.D.; Blanco, E.B.; Lempka, S.F.; Anderson, J.M.; Exner, A.; Gao, J. Combined Radiofrequency Ablation and Doxorubicin-Eluting Polymer Implants for Liver Cancer Treatment. J. Biomed. Mat. Res. 2007, 81, 205-213.
(3) Weinberg, B.; Blanco, E.; Gao, J. Polymer Implants for Intratumoral Drug Delivery and Cancer Therapy. J. Pharm. Sci. In Press.

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