Medical Student Research Fellowship for Summer 2007

Mentor: F. Andrew Kozel, M.D., M.S.C.R.
Department: Psychiatry
Room number: FL13.330
Mail Code: 9119
Phone number: 214-648-5233
E-mail: Andrew.Kozel@utsouthwestern.edu
Project title: fMRI Detection of Deception 2006 UTSW

Human subjects IRB approved project number (where applicable): 102006-050

Animal subjects IRB approved project number (where applicable): N/A

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)
Human-based research

Brief Description of Project:
The purpose of this study is to investigate the areas of brain activation during deception for healthy subjects. By using blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (MRI) during truthful statements and deceptive statements, we hope to replicate our prior work (Kozel FA, Johnson KA, Mu Q, Grenesko E, Laken SJ, and George MS. Detecting Deception using Functional MRI. Biological Psychiatry. 2005; 58(8):605-613) that accurately (90%) identified when subjects were lying and found differences in brain region activation for the group analysis.

The student will assist in recruitment of subjects, screening of subjects, scanning of subjects, and be exposed to fMRI data analysis. This will give the student exposure to the basic elements of imaging research. If the student desires, he/she can potentially start their own side project.

In addition, the student will be exposed to other imaging and brain stimulation protocols presently going on in the lab.

Previous Research Activities or Publications with Medical Students:

Letty J. Revell - Summer Medical Student 2000 - MUSC
Kozel FA, Revell LJ, Lorberbaum JP, Shastri A, Elhai JD, Horner MD, Smith A, Nahas Z, Bohning DE, George MS: A Pilot Study of Functional Magnetic Resonance Imaging Brain Correlates of Deception in Healthy Young Men. Journal of Neuropsychiatry and Clinical Neurosciences. 2004; 16(3):295-305.

Tamara Padgett - Summer Medical Student 2002 - MUSC
Kozel FA, Padgett T, George MS: A Replication Study of the Neural Correlates of Deception. Behavioral Neuroscience. 2004; 118:852-856.

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