Medical Student Research Fellowship for Summer 2007

Mentor: Luis F. Parada, Ph.D.
Department: Developmental Biology
Room number: Building NB, Room 5.208
Mail Code: 9133
Phone number: (214) 648-1822
E-mail: Luis.Parada@UTSouthwestern.edu
Project title: Role of Receptor Tyrosine Kinase in Regulating Adult Neurogenesis and Mood Disorder

Human subjects IRB approved project number (where applicable):

Animal subjects IRB approved project number (where applicable):

Project Type: animal-based research (mice)

Brief Description of Project:

We find that the BDNF receptor, TrkB, is required for hippocampal neurogenesis. Conditional KO's of Trk B in the neurogenic niche results in mice that do not respond to serotonin uptake inhibitors in several behavioral paradigms. We are trying to understand the mechanism.

Previous Research Activities or Publications with Medical Students:

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