Medical Student Research Fellowship for Summer 2007

Mentor: Mamta K. Jain, MD, MPH
Department: Internal Medicine
Room number: Y7.312
Mail Code: 9116
Phone number:214-648-9914
E-mail: mamta.jain@utsouthwestern.edu

Project title: Characterize a cohort of HIV/HCV and HIV/HBV Patients and Evaluate Clincial Outcomes

IRB # 0803-493 and # 033004-099

Human subjects IRB approved project number (where applicable):

Animal subjects IRB approved project number (where applicable): n/a

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

patient-based clinical research

Brief Description of Project: In 2003, an HCV observational study was established and patients who were seen in the HIV/HCV coinfection clinic were asked to consent in the study. Subsequently, a different consent was generated to evaluate clinical outcomes in HIV/HBV coinfected patients in 2004. The role of the student would be to develop a database from the established consents, obtain clinical data from chart review and record in database and then establish a method to assess clinical outcomes (either through chart reviews, phone, etc.). The student will gain experience in developing and using an Access database. They will also gain experience in interpreting clinical labs, liver biopsy data, and radiographic data.

Previous Research Activities or Publications with Medical Students:

1. Rathi Pillai, MSII, 5/04-8/04: Organized HIV/HBV Database on Access, obtained serum samples, analyzed data, wrote abstract, and presented poster in January, 2005 at UT Southwestern.
Publication: Jain M, Opio C, Osuagwu C, Pillai R, Keiser P, Lee W. Do HIV Providers Appropriately Manage Hepatitis B in Coinfected Patients Treated with Antiretroviral Therapy? Clin Infect Dis 2007;44:996-1000.

2. Jonathan Boyd, MSII, 5/06-8/06: Developed and organized an Access database of liver biopsies from 2000- 2005.
3. Shahed Shakouri, MSII, 5/06-8/06: Analyzed a cohort of 1465 HIV-infected patients to determine who had died after 6 years of follow-up. Developed an Access database to record findings. Abstract chosen for an oral presentation at the 45th Annual UT Southwestern Medical Student Research Forum, January, 2007.

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