Medical Student Research Fellowship for Summer 2007
Mentor: Tawanda Gumbo, MD
Department: Medicine/Infectious Diseases
Room number: Y7.312
Mail Code: 9113
Phone number: 214-648 9914
Project title: Pharmacodynamics of antimalaria drugs
Human subjects IRB approved project number (where applicable): NA
Animal subjects IRB approved project number (where applicable): NA
Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)
Basic and translational research
Brief Description of Project:
This project looks at growth of Plasmodium falciparum in the hollow fiber, and the emergence of resistance to chloroquine. The pharmacokinetics-pharmacodynamics of chloroquine linked to emergence of resistance in P falciparum will be identified, and translation of the results to the clinic made using mathematical modeling.
Previous Research Activities or Publications with Medical Students:
Pharmacodynamics of drug resistance to antituberculosis agents rifampin and isoniazid.
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