Medical Student Research Fellowship for Summer 2009
Mentor: Darren K. McGuire
Room number: HA9.133
Mail Code: 9047
Phone number: 214 645 7520
Project title: Role of Gender on Outcomes of Young Acute Myocardial Infarction Patients (VIRGO) Acute Coronary Syndrome Registry
Human subjects IRB approved project number (where applicable): UTSW IRB # 012009-014
Animal subjects IRB approved project number (where applicable): n/a
Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects) Patient-based
Brief Description of Project:
Multi-center NIH-sponsored consecutive patient registry of patients admitted to participating hospitals with a primary diagnosis of acute coronary syndrome or acute myocardial infarctions. The study is designed to explore variations in process of care and outcomes according to selected subgroups, including those with premature coronary artery disease, women, and minority populations.
Previous Research Activities or Publications with Medical Students:
McCollum DL, Greene J, McGuire DK. Severe bradycardia after initiation of bupropion
therapy: A possible drug-drug interaction with metoprolol. Cardiovascular Drugs
and Therapy, 2004; 18:329-30.
Svensson AM, Abrahamsson P, McGuire DK, Dellborg M. Influence of Diabetes on Outcome among Unselected Patients with Acute Coronary Events: A 10-year experience with 4341 patients. Scand Cardiovasc J 2004; 38:229-34.
Svensson AM, McGuire DK, Abrahamsson P, Dellborg M. Glycometabolic state at admission and during hospitalization: Important Risk Marker of Mortality in Diabetes Patients with Acute Coronary Events: a 10 year experience . European Heart J, 2005; 38: 229-34.
Sánchez CD, Newby LK, McGuire DK, Hasselblad V, Feinglos MN, Ohman EM. Diabetes-related knowledge is not associated with measures of risk factor control or cardiac outcomes in patients with diabetes and acute coronary syndromes. Am J Cardiol 2005; 95: 1290-94.
Robinson CR, Martin JL, Zhang L, Canham RM, Abdullah SM, Cigarroa JE, Hillis LD, Murphy SA, McGuire DK, de Lemos JA, Keeley EC. Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction. Am J Cardiol 2006; 97: 7-9.
Khera A, de Lemos JA, Peshock RM, Lo H, Stanek HG, Murphy SA, Wians FH, Grundy SM, McGuire DK. Lack of an Independent Association Between C-Reactive Protein and Subclinical Atherosclerosis: The Dallas Heart Study. Circulation 2006;113 38-43.
Parikh SV, Jacobi JA Chu E, Addo TA, Warner JJ, Delaney KA, McGuire DK, de Lemos JA, Cigarroa JE, Murphy SA, Keeley EC. Treatment Delay in Patients Undergoing Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction: A Key Process Analysis of Patient and Program Factors. Am Heart J 2007;155:290-297.
Yorio J, Viswanathan S, See R, Uchal L, McWhorter JA, Spencer N, Murphy SA, Khera A, de Lemos JA, McGuire DK.The Effect of a Disease Management Algorithm and Dedicated Post-Acute Coronary Syndrome Clinic on Achievement of Guideline Compliance: Results from the Parkland Acute Coronary Event Treatment (PACE-Rx) Study. Journal of Investigative Medicine, 2008; 56:15-25.
Chen K, Lindsey JB, Khera A, de Lemos JA, Goyal A, Vega GL, Murphy SA, Grundy SM, McGuire DK. Independent Associations between Metabolic Syndrome, Diabetes Mellitus and Atherosclerosis: Observations from the Dallas Heart Study. Diab Vasc Dis Res. 2008; 5:96-101.