Medical Student Research Fellowship for Summer 2011
Mentor: Ildiko Lingvay
Room number: U9.134e
Mail Code: 8857
Phone number: 2146482779
Project title: Effect of pioglitazone on pancreatic steatosis and bone turnover
Human subjects IRB approved project number (where applicable): 112008-047
Animal subjects IRB approved project number (where applicable):
Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)
Brief Description of Project: Randomized, double-blind, placebo-controlled study evaluating the effect of pioglitazone 45 mg daily for 1 year on beta-cell function, insulin resistance, pancreatic and hepatic fat content, bone turnover markers, bone mineral density, bone marrow fat content, body fat distribution. To measure these outcomes we use the following tests: frequently sampled intravenous glucose tolerance test, magnetic resonance imaging and spectroscopy, DEXA scan, clinical evaluation.
Previous Research Activities or Publications with Medical Students:
1: Lingvay I, Esser V, Legendre JL, Price AL, Wertz KM, Adams-Huet B, Zhang S, Unger RH, Szczepaniak LS. Noninvasive quantification of pancreatic fat in humans.
J Clin Endocrinol Metab. 2009 Oct;94(10):4070-6. Epub 2009 Sep 22. PubMed PMID: 19773401; PubMed Central PMCID: PMC2758729.
2: Lingvay I, Legendre JL, Kaloyanova PF, Zhang S, Adams-Huet B, Raskin P. Insulin-based versus triple oral therapy for newly diagnosed type 2 diabetes:
which is better? Diabetes Care. 2009 Oct;32(10):1789-95. Epub 2009 Jul 10. PubMed PMID: 19592630; PubMed Central PMCID: PMC2752924.
2009 – student forum, Lori Evans
2010 – EASD, Jaime Legendre
2009 – Student Forum, Jaime Legendre
2009 – Doris Duke Conference, Jaime Legendre
2007 – Student Forum, Bantz, Reed, Garg