Medical Student Research Fellowship for Summer 2011

Mentor:                       Rahul Banerjee, MD         
Department:              Orthopaedic Surgery
Room number:         G8.238
Mail Code:                 8870
Phone number:        214-648-2210
E-mail:                       rahul.banerjee@utsouthwestern.edu

Project #1: (revised) The Role of GPR30 in Fracture Healing

Human subjects IRB approved project number (where applicable):

Animal subjects IRB approved project number (where applicable):  2009-0357

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

Animal-based research

Brief Description of Project:

The purpose of this project is to study the role of the GPR30 estrogen receptor in fracture healing. Using an established mouse femur fracture model, we will compare the healing response of wild type mice to GPR30 knockout mice.

Please see the attached protocol for details of the project.

The medical student will be involved in the breeding and care of the animals, performing the actual surgery (creating femur fractures and fixing them with intramedullar nails) abd analysis of specimens (including immunohistochemistry, analysis of microCT, mechanical strength testing).

Project #2:                Pelvic CT-based Graphical Modeling for Safe Insertion of Screws

Human subjects IRB approved project number (where applicable): 082010-113

Animal subjects IRB approved project number (where applicable): 

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

Patient-based research

Brief Description of Project:

The purpose of this study was to identify and describe a safe, extra-articular pathway for insertion of a screws for fracture fixation based on computer modeling derived from CT scans. The medical student, Soham Banerjee, designed the main computer algorithm for the software and he continues to work with me on revising this and applying it to the pelvic CT scans.

Project #3:    Pelvic CT-based Graphical Modeling for Safe Insertion of Screws

Human subjects IRB approved project number (where applicable): 082010-113

Animal subjects IRB approved project number (where applicable): 

Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)

Patient-based research

Brief Description of Project:

The purpose of this study was to identify and describe a safe, extra-articular pathway for insertion of a screws for fracture fixation based on computer modeling derived from CT scans. The medical student, Soham Banerjee, designed the main computer algorithm for the software and he continues to work with me on revising this and applying it to the pelvic CT scans.

Previous Research Activities or Publications with Medical Students:

Abstract already submitted from this project to the OTA:

Soham Banerjee, BS; Cameron Sadeghi, MD; Adam J. Starr, MD; Rahul Banerjee, MD. Pelvic CT-Based Graphical Modeling for Safe Insertion of Anterior Column Screws, Submitted for Orthopaedic Trauma Association Annual Meeting, 2011
Soham Banerjee, BS; Cameron Sadeghi, MD; Adam J. Starr, MD; Rahul Banerjee, MD. Pelvic CT-Based Graphical Modeling for Safe Insertion of Anterior Column Screws, Submitted for Texas Orthopaedic Association Annual Meeting, 2011

Advisor to Ryan Taylor, UTSW Class of 2010

Publications with Ryan Taylor:
Banerjee R, Chao J, Sadeghi C, Taylor R, Nickisch F, Fractures of the calcaneal tuberosity treated with suture fixation through bone tunnels, J Orthop Trauma, Accepted for publication.

Banerjee R, Chao J, Taylor R, Siddiqi A, Management of calcaneal tuberosity fractures, Submitted to J Am Acad Ortho Surg.