2012projectindex057DiMaio

Medical Student Research Fellowship for Summer 2012

Mentor: J. Michael DiMaio, MD
Department: Cardiothoracic Surgery
Room number: HA9.134
Mail Code: 8879
Phone number: 214-645-7731
E-mail: Michael.dimaio@utsouthwestern.edu, Leah.gaither@utsouthwestern.edu
Project title:

1. Infective endocarditis: Clinical Care and Results of Surgical Management (IRB 062010- 009)
Parkland Memorial Hospital has a large population of immigrants from third-world countries. Due to the continued presence of rheumatic heart disease and the sequela of valve abnormalities as well as the intravenous drug abuse populations, there is a large amount of endocarditis that presents at the hospital. A review of the survival of these patients represents a survival in the cardiac surgical department that is far superior to other series in literature. A very thorough review of the microbiology indicates that for surgery, valve repair versus replacement and the echocardiographic data can be compared to other series such as the ICE database (that stands for the International Consortium for Endocarditis).

2. LASER LEAD EXTRACTION (IRB pending)
With increasing number of electrophysiological devices, including pacemakers and ICDs, there is increasing requirement to remove these long-term devices with novel methods. Newer methods involve using excimer lasers to help excise these leads in the operating room. Some institutions have utilized this in the catheterization lab, but it is felt by our institution that the safest location is in the operating room with the combined expertise of cardiology and thoracic surgery.

3. AIRWAY AND LASER STENTS (IRB pending)
UT Southwestern represents one of the largest centers for aggressive airway and esophageal interventional management. The utilization of holmium YAG lasers and stents for benign and malignant disease are reviewed in this series. Again, the indications and complications of this will provide insight for other centers and other series.

Project Type – all patient based

Previous Research Activities or Publications with Medical Students:

Infective Endocarditis: Clinical Course and Results of Surgical Management

Pain Management Techniques used in the Postoperative Period following Thoracotomy Procedures –

A Retrospective Analysis and Follow up

Clinical Management of Laryngotracheal Trauma: Case Report and Literature Review
Lung Cancer in Heart Transplant Patients: The Use of CT Screening
Traumatic Aortic Injury: Management of Blunt Aortic Injury – A Paradigm Shift?
Pleural Effusions: Effective Palliation of Malignant Pleural Effusions With the Pleurx Catheter
Esophageal Cancer: Clinical Impact of Combined Modality Therapy for Esophageal Cancer
Renal Cell Carcinoma: Contemporary Techniques Improving the Safety of Surgical Management of Tumor Thrombi

Early steroid withdrawal improves late survival after heart transplantation: 14 year results
Renal function is preserved following heart transplantation using IL-2 receptor blockade

		G. Wheatley, C. W. Yancy, M. A. Wait, D. M. Meyer, M. E. Jessen, M. C. Paul, P. Kaiser, R. A. Bhojani, M. Drazner, W. S. Ring and J. M. DiMaio Renal function is preserved following heart transplantation using IL-2 receptor blockade. J of Heart and Lung Transplantation. Volume 23, Issue 2, Supplement 1, February 2004, Page S140.

		D.H. Rosenbaum, R.A. Bhojani, P. Kaiser, E. Dikmen, M.C. Paul, C. Yancy, W.S. Ring and J.M. DiMaio. Routine chest CT screening in high risk cardiac transplant patients may improve survival. J of Heart and Lung Transplantation.Volume 24, Issue 2, Supplement 1, February 2005, Pages S47-S48.

		Bhojani RA, Rosenbaum DH, Dikmen E, Paul MC, Atkins BZ, Zonies D, Estrera AS, Wait MA, Meyer DM, Jessen ME, DiMaio JM. Contemporary Assessment of Laryngotracheal Trauma. J Thoracic and Cardiovascular Surgery. Volume 130, Issue 2, August 2005, 426-432.

		Khwaja S, Rosenbaum DH, Paul MC, Bhojani RA, Estrera AS, Wait MA, DiMaio JM. Surgical treatment of thoracic empyema in HIV-infected patients: Severity and treatment modality is associated with CD4 status. Chest. 2005; 128:246-249.

		Rosenbaum DH, Bhojani RA, Dikmen E, Paul MC, Wait MA, Meyer DM, Jessen ME, Yancy CW, Ring WS, DiMaio JM. Routine chest CT screening in high risk cardiac transplant patients may improve survival. J of Heart and Lung Transplantation. 2005; 24(12): 2043-2047.

		Sallach SM, Dobrilovic N, Hirsch BR, Paul MC, Cabell C, Pappas P, DiMaio JM, Peterson GE. Echocardiographic outcome predictors in surgically treated patients with infective endocarditis. J Am Coll Cardiol. 2005; 45(3):280A.

		Dobrilovic N, Hirsch BR, Sallach SM, Paul MC, Peterson GE, Wait MA, Jessen ME, Ring WS, Cabell C, Pappas P, DiMaio JM. Outcomes and risk assessment of diabetic patients treated surgically for infective endocarditis. Circulation. 2005; 111(20):316E.

		Dobrilovic N, Hirsch BR, Sallach SM, Paul MC, White MD, Peterson GE, Wait MA, Ring WS, Jessen ME, Pappas P, Cabell C, DiMaio JM. Predictors of adverse and favorable outcomes in patients undergoing surgery for infective endocarditis. J Cardiovasc Surg. 2005.

		Lubahn JG, Sagalowsky AI, Rosenbaum DH, Dikmen E, Bhojani RA, Paul MC, Dolmatch BL, Josephs SC, Benaim E, Levinson BS, Hamilton TT, Wait MA, Ring WS, DiMaio JM. Contemporary techniques improving the safety of surgical management of tumor thrombi in renal cell carcinoma. Accepted for publication in the J Thoracic and Cardiovascular Surgery.

		Rosenbaum DH, Adams BC, Mitchell JD, Jessen ME, Paul MC, Kaiser PA, Pappas PA, Meyer DM, Wait MA, Drazner MH, Yancy CW, Ring WS, DiMaio JM. Effects of early steroid withdrawal after heart transplantation. Accepted for publication in the Annals of Thoracic Surgery.

		Rosenbaum DH, Mitchell JD, Adams BC, Paul MC, Jessen ME, Kaiser PA, Meyer DM, Wait MA, Drazner MH, Yancy CW, Ring WS, DiMaio JM. Effects of Basiliximab induction therapy at mid-term follow up in cardiac allograft recipients. Submitted to the Journal of Heart and Lung Transplantation.