Medical Student Research Fellowship for Summer 2012
Mentor: Karanjit S Kooner MD
Room number; E5-406.
Mail Code: 9057
Phone number: 214-648-4733
Project title: Dallas Glaucoma Registry
Student ; Nathan Markel.
Human subjects IRB approved project number (where applicable): VA IRB # 07-049
Animal subjects IRB approved project number (where applicable): N/A
Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects): Patient based research.
Brief Description of Project:
Glaucoma is a multifactorial disease characterized by progressive optic neuropathy, corresponding visual field (VF) defects, with or without elevated intraocular pressure (IOP). The disease may either be primary or secondary in origin. Predisposing elements have both ocular (elevated IOP, myopia, trauma) and systemic (race, older age, hypertension, diabetes) risk factors.
The weaknesses of major eye trials include small number of patients without adequate racial representations. The glaucoma population in Dallas (UTSWMV, PMH, VA) approximates 15,000 and tends to fulfill these requirements quiet adequately.
We have collected data on approximately 2000 patients at the VA Hospital so far. There is a need for 500 more patients to fulfill statistical analysis requirements. This is a retrospective chart review study and the data collection forms are in use. IRB approval at the VA Hospital is current.
Specific objectives: 1. what role does raceplay in the presenting features of glaucoma and overall management?
2. Would early surgical intervention provide better visual outcomes?
Role of students: 1. the first few days will be spent in getting familiarized with clinical activates in ophthalmology. They will spend time with us in clinics and operating rooms. Students will observe how we interview patients, check vision, intraocular pressure, central corneal thickness, gonioscopy, fundoscopy and slit lamp examination. Our technicians will show the students how they perform visual fields, ocular coherent tomography and fundus photos. In the OR, students will observe various glaucoma and cataract procedures.
2. The students will be taught how to use our data collection form and how information is extracted from patient charts. They will be able to read visual fields and optic disk features.
3. Each student will be given a separate project within our main area of research and will be supervised regularly. We expect them to prepare an abstract for submission at a national eye meeting.
Previous Research Activities or Publications with Medical Students: