Mentor: Don Rockey
Department: Division of Digestive and Liver Disease
Room number: K5.140
Mail Code: 8887
Phone number: 214-645-6283
E-mail: don.rockey@utsouthwestern.edu
Project title: Studies in Chronic Liver Disease
Human subjects IRB approved project number (where applicable): (Multiple)
Animal subjects IRB approved project number (where applicable): N/A
Project Type (patient-based research, animal-based research, or basic research; this characterization is only to permit a general classification for grouping similar types of projects)
Patient-based research
Brief Description of Project:
Our group has been highly active in studies focused on chronic liver disease. These studies range from retrospective database studies (we have a dedicated database that contains 1208 patients admitted to Parkland Memorial Hospital with a diagnosis of cirrhosis. We have also begun working the development on a chronic liver disease study unit. This will provide a structure to perform prospective randomized controlled trials. Topics that have been analyzed retrospectively include the outcomes in patients admitted with hepatic encephalopathy, the outcomes of patients with variceal hemorrhage over time, hepatorenal syndrome, our experience with prophylactic therapy in patients with esophageal varices, and many others. Our group has generated over 10 abstracts in this area in 2007 and 2008.
Previous Research Publications with Housestaff (last 7 years only):
*liver disease related
*Lyles T (Resident), Naik S, Rockey DC. Outcomes in cirrhotics with upper gastrointestinal hemorrhage - importance of the etiology of bleeding. (DDW 2009).
*Naik S (Resident), Kumar A, Rockey DC. Outcomes of cirrhotics admitted with altered mental status. (DDW 2009).
Duraiswamy S (Resident), Schmulewitz N, Rockey DC. The role of techneticum-99 labeled erythrocyte scintigraphy in the evaluation of patients with lower gastrointestinal bleeding. (DDW 2009).
Singh S (Resident), Tang S, Sree J, Lara LF, Rockey DC. The clinical significance of elevated levels of CA 19-9. (DDW 2009).
Melo S (Fellow), Bhore R, Rockey DC. The use of clinical parameters to predict need for endoscopic therapy in patients with upper gastrointestinal hemorrhage. (DDW 2009).
Balderas V (Fellow), Lara LF, Rockey DC. The safety of endoscopy in patients with upper GI bleeding and a low hematocrit. (DDW 2009).
Melo S (Fellow), Bhore R, Rockey DC. Predicting the cause of upper gastrointestinal hemorrhage: the importance of clinical experience. (DDW 2009).
*Maddur H (Resident), Naik S, Rockey DC. Adherence and adequacy of therapy for esophageal varices prophylaxis. MS Submitted (2008).
*Naik S (Resident), Maddur H, Rockey DC. Emergence of sepsis as a leading cause of mortality in cirrhotics. MS Submitted (2008).
*Padda MS (Fellow), Singh S, Tang S, Rockey DC. Liver test patterns in patients with acute calculous cholecystitis and/or choledocholithiasis. MS Submitted (2008).
Weinstein DH (Resident), Lee SY, Tang SJ, Sree J, Lara LF, Rockey DC. Comparison of endoscopic hemostasis management preferences for nonvariceal GI hemorrhage among trainees and faculty members. MS Submitted (2008)
Bachir N (Fellow), Gokaslan T, Rockey DC. The incidence of celiac disease in a Hispanic population in a southwestern urban medical center. MS Submitted (2008).
Shah J (Fellow), Hynan L, Rockey DC. Management of small polyps detected by screening CT colonography: Patient and physician preferences. MS Submitted (2008).
Scales C (Student), Fein S, Muir A, Rockey DC. Clinical utilization of digital rectal examination and fecal occult blood testing upon hospital admission. Journal of Clinical Gastroenterology 40:913-918, 2006.
Green BT (Fellow), Rockey DC (Corresponding author), Portwood GL, Tarnasky PR, Guarisco S, Branch MS, Leung J, Jowell P. Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage: a randomized controlled trial. American Journal of Gastroenterology 100:2395-2402, 2005.
Green BT (Fellow), Rockey DC. Gastrointestinal endoscopic evaluation of premenopausal women with iron deficiency anemia. Journal of Clinical Gastroenterology 38:104-109, 2004.
Dobozi B (Fellow), Rockey DC. Diffuse colonic hemangiomatosis. Gastrointestinal Endoscopy 60:799, 2004.
Ioannou G (Resident), Doust J, Rockey DC. Terlipressin for acute oesophageal variceal hemorrhage: A systematic review and meta-analysis. Alimentary Pharmacology and Therapeutics 17:53-64, 2003.
Schmulewitz N (Fellow), Fisher DA, Rockey DC. Early colonoscopy for acute lower gastrointestinal bleeding predicts shorter hospital stay: a retrospective study of experience in a single center. Gastrointestinal Endoscopy 58:841-846, 2003.
Ioannou G (Resident), Spector J, Scott K, Rockey DC. Prospective evaluation of a clinical guideline for the diagnosis and management of iron-deficiency anemia. American Journal of Medicine 113: 281-287, 2002.