Associate Dean for Academic Planning
Born
December 10, 1944, Kansas City, Missouri
Education
1962-66 Rockhurst College, B.A. (magna cum laude) Major in
Biology, Minor in Chemistry
1966-70 University of Kansas School of Medicine, M.D.
Professional Appointments
1970-71 Medical Intern, University of Kansas Medical Center
1971-72 Resident in Internal Medicine, University of Kansas Medical Center
1972-74 Chief Medical Officer, St. Louis Armed Forces Examination and Entrance Station
1974-76 Research Fellow, Department of Internal Medicine, University of Texas Health Science Center at Dallas, Southwestern Medical School
1975-76 Instructor, Department of Internal Medicine, University of Texas Health Science Center at Dallas, Southwestern Medical School
1976-80 Assistant Professor, Department of Internal Medicine, University of Texas Health Science Center at Dallas, Southwestern Medical School
1980-83 Editorial Board, Journal of Clinical Endocrinology and Metabolism
1980-89 Associate Professor, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas
1983-86 Associate Dean for Medical Education, University of Texas Health Science Center at Dallas, Southwestern Medical School
1986- Associate Dean for Academic Planning, University of Texas Southwestern Medical Center at Dallas
1989- Professor, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas
1992-1994 Editorial Board Journal of Andrology
1994- Diana and Richard C. Strauss Professor in Biomedical Research, University of Texas Southwestern Medical Center at Dallas
1995-1997 Interim Chief, Division of Endocrinology and Metabolism
1995- Director, Training Program in Endocrinology and Metabolism
1997- Chief, Clinical Endocrinology and Metabolism
Professional Societies
Alpha Omega Alpha
American Association of Clinical Endocrinologists
American Federation for Clinical Research
American College of Endocrinology, Fellow
American College of Physicians, Fellow
American Society for Clinical Investigation
Diplomate, American Board of Internal Medicine and Subspecialty of
Endocrinology and Metabolism
Endocrine Society
PUBLICATIONS
1. Anggard E, Bohman SO, Griffin JE, Larson C, Maunsbach AB 1972 Subcellular localization of the prostaglandin system in the rabbit renal papilla. Acta Physiol Scand 84:231-246
2. Moore RJ, Griffin JE, Wilson JD 1975 Diminished 5 -reductase activity in extracts of fibroblasts cultured from patients with familial incomplete male pseudohermaphroditism, type 2. J Biol Chem 250:7168-7172
3. Griffin JE, Punyashthiti K, Wilson JD 1976 Dihydrotestosterone binding by cultured human fibroblasts: Comparison of cells from control subjects and from patients with hereditary male pseudohermaphroditism due to androgen resistance. J Clin Invest 57:1342-1351
4. Griffin JE, Edwards C, Madden JD, Harrold MJ, Wilson JD 1976 Congenital absence of the vagina. The Mayer-Rokitanksy-Kuster-Hauser syndrome. Ann Intern Med 85:224-236
5. Griffin JE, Wilson JD 1976 Biochemical and genetic analysis of androgen-mediated virilization of the wolffian ducts and urogenital sinus. In: James VHT (ed) Proceedings of the Vth International Congress of Endocrinology, Hamburg, July 18-24, Vol. 1, Excerpta Medica International Congress Series No. 402 Endocrinology, pp 266-269
6. Griffin JE, Wilson JD 1977 Studies on the pathogenesis of the incomplete forms of androgen resistance in man. J Clin Endocrinol Metab 45:1137-1143
7. Walsh PC, Wilson JD, Allen TD, Madden JD, Porter JC, Neaves WB, Griffin JE, Goodwin WE 1978 Clinical and endocrinological evaluation of patients with congenital microphallus. J Urol 120:90-95
8. Collier ME, Griffin JE, Wilson JD 1978 Intranuclear binding of [3H]dihydrotes- tosterone by cultured human fibroblasts. Endocrinology 103:1499-1505
9. Griffin JE, Wilson JD 1978 Hereditary male pseudohermaphroditism. Clin Obstet Gynaec 5:457-479
10. Fisher LK, Kogut MD, Moore RJ, Goebelsmann U, Weitzman JJ, Isaacs H Jr, Griffin JE, Wilson JD 1978 Clinical, endocrinological, and enzymatic characterization of two patients with 5_-reductase deficiency: Evidence that a single enzyme is responsible for the 5 -reduction of cortisol and testosterone. J Clin Endocrinol Metab 47:653-664
11. Leshin M, Griffin JE, Wilson JD 1978 Hereditary male pseudohermaphroditism
associated with an unstable form of 5 -reductase. J Clin Invest 62:685-691
12. Boyar RM, Moore RJ, Rosner W, Aiman J, Chipman J, Madden JD, Marks JF, Griffin JE 1978 Studies of gonadotropin-gonadal dynamics in patients with androgen insensitivity. J Clin Endocrinol Metab 47:1116-1122
13. Aiman J, Griffin JE, Gazak JM, Wilson JD, MacDonald PC 1979 Androgen insensitivity as a cause of infertility in otherwise normal men. N Engl J Med 300:223-227
14. Griffin JE 1979 Testicular feminization associated with a thermolabile androgen receptor in cultured human fibroblasts. J Clin Invest 64:1624-1631
15. Griffin JE, Wilson JD 1979 Genetic and molecular characterization of androgen resistance syndromes in man. In: Vallet HL, Porter IH (eds), Genetic Mechanisms of Sexual Development, Academic Press, New York, pp 129-147
16. Wilson JD, Griffin JE, George FW 1979 The mechanism of phenotypic sex differentiation. Arthritis Rheum 22:1275-1283
17. Imperato-McGinley J, Peterson RE, Leshin M, Griffin JE, Cooper G, Draghi S, Berenyi M, Wilson JD 1980 Steroid 5 -reductase deficiency in a 65-year-old male pseudohermaphrodite: The natural history, ultrastructure of the testis and evidence for inherited enzyme heterogeneity. J Clin Endocrinol Metab 50:15-22
18. Neaves WB, Griffin JE, Wilson JD 1980 Sexual dimorphism of the phallus in spotted hyaena. J Reprod Fertil 59:509-513
19. Griffin JE, Wilson JD 1980 The testis. In: Bondy PK, Rosenberg LE (eds), Metabolic Control and Disease, 8th Edition. WB Saunders, Philadelphia, Chap 22, pp 1535-1578
20. Wilson JD, Griffin JE, George FW 1980 Sexual differentiation: Early hormone synthesis and action. Biol Reprod 22:9-17
21. Griffin JE, Wilson JD 1980 The syndromes of androgen resistance. N Engl J Med 302:198-209
22. Wilson JD, Griffin JE 1980 Disorders of sexual differentiation. In: Isselbacher KJ, Adams RA, Braunwald E, Petersdorf RG, Wilson JD (eds), Harrison's Principles of Internal Medicine, 9th Edition, McGraw-Hill, New York, Chap 344, pp 1794-1808
23. Griffin JE, Wilson JD 1980 Diseases of the testes. In: Isselbacher KJ, Adams RA, Braunwald E, Petersdorf RG, Wilson JD (eds), Harrison's Principles of Internal Medicine, 9th Edition, McGraw-Hill, New York, Chap 341, pp 1764-1775
24. Griffin JE 1980 Androgen resistance syndromes. In: Cumming IA, Funder JW, Mendelsohn FAO (eds), Endocrinology 1980, Proceedings of the VI International Congress of Endocrinology, Melbourne, Australia, February 10-16, 1980, Australian Academy of Science, Canberra, pp 567-570
25. Wilson JD, Griffin JE 1980 The use and misuse of androgens. Metabolism 29:1278-1295
26. Wilson JD, Griffin JE, George FW, Leshin M 1981 The role of gonadal steroids in sexual differentiation. Recent Prog Horm Res 37:1-39
27. Wilson JD, George FW, Griffin JE 1981 The hormonal control of sexual development. Science 211:1278-1284
28. Griffin JE, Allman DR, Durrant JL, Wilson JD 1981 Variation in steroid 5 -reductase activity in cloned human skin fibroblasts. J Biol Chem 256:3662-3666
29. Wilson JD, Griffin JE, Leshin M, George FW 1981 Role of gonadal hormones in development of the sexual phenotypes. Hum Genet 58:78-84
30. George FW, Griffin JE, Leshin M, Wilson JD 1981 Endocrine control of sexual differentiation in the human. In: Novy MJ, Resko JA (eds), Fetal Endocrinology, Academic Press, New York, pp 341-357
31. Aiman J, Griffin JE 1982 The frequency of androgen receptor deficiency in infertile men. J Clin Endocrinol Metab 54:725-732
32. Griffin JE, Durrant JL 1982 Qualitative receptor defects in families with androgen resistance: Failure of stabilization of the fibroblast cytosol androgen receptor. J Clin Endocrinol Metab 55:465-474
33. Griffin JE, Leshin M, Wilson JD 1982 Androgen resistance syndromes. Am J Physiol 243 (Endocr.Metab.6):E81-E87
34. Wilson JD, Griffin JE, Leshin M, MacDonald PC, 1983 The androgen resistance syndromes: 5 -reductase deficiency, testicular feminization, and related disorders. In: Stanbury JB, Wyngaarden JB, Fredrickson DS, Goldstein JL, Brown MS (eds), The Metabolic Basis of Inherited Disease, McGraw-Hill, New York, Chap 48, pp 1001-1026
35. Wilbert DM, Griffin JE, Wilson JD 1983 Characterization of the cytosol androgen receptor of the human prostate. J Clin Endocrinol Metab 56:113-120
36. Griffin JE, Leshin M, Wilson JD 1983 Androgen resistance syndromes. In: Krieger DT, Bardin CW (eds), Current Therapy in Endocrinology 1983-1984, BC Decker Inc, Philadelphia, pp 391-394
37. Griffin JE 1983 The androgen resistance syndromes. In: Chabner BA (ed), Rational Basis for Chemotherapy, AR Liss Inc, New York, pp 137-151
38. El Awady MK, Allman DR, Griffin JE, Wilson JD 1983 Expression of a mutant androgen receptor in cloned fibroblasts derived from a heterozygous carrier for the syndrome of testicular feminization. Am J Hum Genet 35:376-384
39. Griffin JE, Wilson JD 1983 Disorders of the testis. In: Petersdorf RG, Adams RD, Braunwald E, Isselbacher KJ, Martin JB, Wilson JD (eds), Harrison's Principles of Internal Medicine, 10th Edition, McGraw-Hill, New York, Chap 117, pp 689-700
40. Wilson JD, Griffin JE 1983 Disorders of sexual differentiation. In: Petersdorf RG, Adams RD, Braunwald E, Isselbacher KJ, Martin JB, Wilson JD (eds), Harrison's Principles of Internal Medicine, 10th Edition, McGraw-Hill, New York, Chap 120, pp 724-739
41. Wilson JD, Griffin JE, George FW, Leshin M 1983 The endocrine control of male phenotypic development. Aust J Biol Sci 36:101-128
42. Griffin JE, Zerwekh JE 1983 Impaired stimulation of 25-hydroxyvitamin D-24- hydroxylase in fibroblasts from a patient with vitamin D-dependent rickets, type II. J Clin Invest 72:1190-1199
43. Kovacs WJ, Griffin JE, Wilson JD 1983 Transformation of human androgen receptors to the deoxyribonucleic acid-binding state. Endocrinology 113:1574-1581
44. Wilson JD, Griffin JE, George FW, Leshin M 1984 Recent studies on the endocrine control of male phenotypic development. In: Serio M, Motta M, Zanisi M, Martini L (eds), Sexual Differentiation: Basic and Clinical Aspects, Raven Press, New York, Vol 11, pp 223-232
45. Allen TD, Griffin JE 1984 Endocrine studies in patients with advanced hypospadi as. J Urol 131:310-314
46. Kovacs WJ, Griffin JE, Weaver DD, Carlson BR, Wilson JD 1984 A mutation that causes lability of the androgen receptor under conditions that normally promote transformation to the DNA-binding state. J Clin Invest 73:1095-1104
47. Price P, Wass JAH, Griffin JE, Leshin M, Savage MO, Large DM, Bu'Lock DE, Anderson DC, Wilson JD, Besser GM 1984 High dose androgen therapy in male pseudohermaphroditism due to 5 -reductase deficiency and disorders of the androgen receptor. J Clin Invest 74:1496-1508
48. Wilson JD, Carlson BR, Weaver DD, Kovacs WJ, Griffin JE 1984 Endocrine and genetic characterization of cousins with male pseudohermaphroditism: Evidence that the Lubs phenotype can result from a mutation that alters the structure of the androgen receptor. Clin Genet 26:363-370
49. Wilson JD, Griffin JE, George FW, Leshin M 1984 Androgen action and the mechanisms of hormone resistance. In: Isselbacher KJ (ed), Medicine, Science, and Society: Symposia Celebrating The Harvard Medical School Bicentennial, John Wiley and Sons, New York, Chap 26, pp 463-481
50. Griffin JE, Leshin M, Kovacs WJ, Wilson JD 1984 The syndromes of androgen resistance. In: Labrie F, Proulx L (eds), Proceedings of the VIIth International Congress of Endocrinology, Quebec, Canada, July 1-7, Elsevier Science Publishers, Amsterdam, pp 849-852
51. Smallridge RC, Vigersky R, Glass AR, Griffin JE, White BJ, Eil C 1984 Androgen receptor abnormalities in identical twins with oligospermia: Clinical and biochemical studies. Am J Med 77:1049-1054
52. Griffin JE, Wilson JD 1984 Disorders of androgen receptor function. Ann N Y Acad Sci 438:61-71
53. Griffin JE, Leshin M, Wilson JD 1985 Androgen resistant syndromes. In: Krieger DT, Bardin CW (eds), Current Therapy in Endocrinology and Metabolism 1985-1986, BC Decker Inc, Philadelphia, pp 188-190
54. Griffin JE 1985 Dynamic tests of endocrine function. In: Wilson JD, Foster DW (eds), Williams Textbook of Endocrinology, 7th Edition, WB Saunders, Philadelphia, pp 147-154
55. Griffin JE, Wilson JD 1985 Disorders of the testis and male reproductive tract. In: Wilson JD, Foster DW (eds), Williams Textbook of Endocrinology, 7th Edition, WB Saunders, Philadelphia, pp 259-311
56. Carr BR, Griffin JE 1985 Fertility control and its complications. In: Wilson JD, Foster DW (eds), Williams Textbook of Endocrinology, 7th Edition, WB Saunders, Philadelphia, pp 452-475
57. Griffin JE 1985 The dilemma of abnormal thyroid function tests - Is thyroid disease present or not? Am J Med Sci 289:76-88
58. Griffin JE, Kovacs WJ, Wilson JD 1985 Characteristics of androgen resistance. In: Bruchovsky N, Chapdelaine A, Neumann F (eds), Regulation of Androgen Action, The Proceedings of an International Symposium, Montreal 1984, Congressdruck R Bruckner, Berlin, pp 127-131
59. Wilson CM, Griffin JE, Reynolds RC, Wilson JD 1985 The interaction of androgen and thyroid hormones in the submandibular gland of the genetically hypothyroid (hyt/hyt) mouse. Endocrinology 116:2568-2577
60. Wilson JD, Griffin JE 1985 Mutations that impair androgen action. Trends Genet 1:335-339
61. Costin G, Roe TF, Griffin JE 1985 Prevalence of androgen receptor abnormalities in patients with male pseudohermaphroditism and normal testosterone synthesis. J Pediatr Endocrinol 1:197-202
62. Griffin JE, Wilson JD 1986 Disorders of sexual differentiation. In: Walsh PC, Gittes RF, Perlmutter AD, Stamey RA (eds), Campbell's Urology, WB Saunders, Philadelphia, pp 1819-1855
63. George FW, Griffin JE 1986 The ontogeny of male sexual development. In: Male Reproductive Dysfunction: Diagnosis and Management of Hypogonadism, Infertility, and Impotence, Marcel Dekker, New York, pp 127-142
64. Kovacs WJ, Griffin JE, Wilson JD 1986 Androgen resistance in man. In: Chrousos GP, Loriaux DL Lipsett MB (eds), Steroid Hormones Resistance, Plenum Publishing, New York, pp 257-267
65. Nagel RA, Lippe BM, Griffin JE 1986 Androgen resistance in the neonate: Use of hormones of hypothalamic-pituitary-gonadal axis for diagnosis. J Pediatr 109:486-488
66. Johnson L, George FW, Neaves WB, Rosenthal IM, Christensen RA, Decristoforo A, Schweikert H-U, Sauer MV, Leshin M, Griffin JE, Wilson JD 1986 Characterization of the testicular abnormality in 5 -reductase deficiency. J Clin Endocrinol Metab 63:1091-1099
67. Casey ML, Griffin JE, Korte K, Mitchell MD, MacDonald PC 1986 Responses of human amnion cells in culture to 1,25-dihydroxycholecalciferol: Increased 25-hydroxycholecalciferol 24-hydroxylase activity and prostaglandin E2 formation. Am J Obstet Gynecol 155:1272-1275
68. Griffin JE, Wilson JD 1987 Disorders of the testis. In: Braunwald E, Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS (eds), Harrison's Principles of Internal Medicine, 11th Edition, McGraw-Hill, New York, Chap 330, pp 1807-1818
69. Wilson JD, Griffin JE 1987 Disorders of sexual differentiation. In: Braunwald E, Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS (eds), Harrison's Principles of Internal Medicine, 11th Edition, McGraw-Hill, New York, Chap 333, pp 1840-1853
70. Griffin JE 1987 Diagnosis and management of male infertility. Adv Intern Med 32:259-282
71. Schweikert H-U, Weissbach L, Stangenberg C, Leyendecker G, Kley H-K, Griffin JE, Wilson JD 1987 Clinical and endocrinological characterization of two subjects with Reifenstein syndrome associated with qualitative abnormalities of the androgen receptor. Horm Res 25:72-79
72. Grino PB, Griffin JE, Wilson JD 1987 Transformation of the androgen receptor to the deoxyribonucleic acid-binding state: Studies in homogenates and intact cells. Endocrinology 120:1914-1920
73. Wieacker P, Griffin JE, Wienker T, Lopez JM, Wilson JD, Breckwoldt M 1987 Linkage analysis with RFLPs in families with androgen resistance syndromes: Evidence for close linkage between the androgen receptor locus and the DXS1 segment. Hum Genet 76:248-252
74. Griffin JE, Wilson JD 1987 Syndromes of androgen resistance. Hosp Pract 22:159-176
75. Grino PB, Griffin JE, Cushard WG Jr, Wilson JD 1988 A mutation of the androgen receptor associated with partial androgen resistance, familial gynecomastia, and fertility. J Clin Endocrinol Metab 66:754-761
76. Griffin JE 1988 Southwestern Internal Medicine Conference: Management of thyroid nodules. Am J Med Sci 296:336-347
77. Wilson CM, Kimberlin DF, Griffin JE, Wilson JD 1988 Specificity of androgen resistance in Mus caroli kidney. Biochem Genet 26:705-716
78. Grino PB, Isidro-Gutierrez RF, Griffin JE, Wilson JD 1989 Androgen resistance associated with a qualitative abnormality of the androgen receptor and responsive to high dose androgen therapy. J Clin Endocrinol Metab 68:578-584
79. Griffin JE, Wilson JD 1989 The androgen resistance syndromes: 5 -reductase deficiency, testicular feminization, and related syndromes. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds), The Metabolic Basis of Inherited Disease, 6th Edition, McGraw-Hill, New York, pp 1919-1944
80. Meyers-Wallen VN, Wilson JD, Griffin JE, Fisher S, Moorhead PH, Goldschmidt MH, Haskins ME, Patterson DF 1989 Testicular feminization in a cat. J Am Vet Med Assoc 195:631-634
81. Grino PB, Griffin JE, Wilson JD 1990 Testosterone at high concentrations interacts with the human androgen receptor similarly to dihydrotestosterone. Endocrinology 126:1165-1172
82. Marcelli M, Tilley WD, Wilson CM, Wilson JD, Griffin JE, McPhaul MJ 1990 A single nucleotide substitution introduces a premature termination codon into the androgen receptor gene of a patient with receptor-negative androgen resistance. J Clin Invest 85:1522-1528
83. Griffin JE 1990 Review: Hypothyroidism in the elderly. Am J Med Sci 299:334- 345
84. Grino PB, Griffin JE, Wilson JD 1990 Androgen resistance due to decreased amoun ts of androgen receptor: A reinvestigation. J Steroid Biochem 35:647-654
85. Marcelli M, Tilley WD, Wilson CM, Griffin JE, Wilson JD, McPhaul MJ 1990 Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: Premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance. Mol Endocrinol 4:1105-1116
86. Guerami A, Griffin JE, Kovacs WJ, Grino PB, MacDonald PC, Wilson JD 1990 Estrogen and androgen production rates in two brothers with Reifenstein syndrome. J Clin Endocrinol Metab 71:247-251
87. Carpenter TO, Imperato-McGinely J, Boulware SD, Weiss RM, Shackleton C, Griffin JE, Wilson JD 1990 Variable expression of 5 -reductase deficiency: Presentation with male phenotype in a child of Greek origin. J Clin Endocrinol Metab 71:318-322
88. Marcelli M, Zoppi S, Grino PB, Griffin JE, Wilson JD, McPhaul MJ 1991 A mutation in the DNA-binding domain of the androgen receptor gene causes complete testicular feminization in a patient with receptor-positive androgen resistance. J Clin Invest 87:1123-1126
89. McPhaul MJ, Marcelli M, Tilley WD, Griffin JE, Isidro-Guiterrez RF, Wilson JD 1991 Molecular basis of androgen resistance in a family with a qualitative abnormality of the androgen receptor and responsive to high-dose androgen therapy. J Clin Invest 87:1413-1421
90. Marcelli M, Tilley WD, Zoppi S, Griffin JE, Wilson JD, McPhaul MJ 1991 Androgen resistance associated with a mutation of the androgen receptor at amino acid 772 (Arg_Cys) results from a combination of decreased messenger ribonucleic acid levels and impairment of receptor function. J Clin Endocrinol Metab 73:318-325
91. Griffin JE, Wilson JD 1991 Disorders of the testis. In: Wilson JD, Braunwald E, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Root RK (eds), Harrison's Principles of Internal Medicine, 12th Edition, McGraw-Hill, New York, Chap 321, pp 1765-1776
92. Wilson JD, Griffin JE 1991 Disorders of sexual differentiation. In: Wilson JD, Braunwald E, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Root RK (eds), Harrison's Principles of Internal Medicine, 12th Edition, McGraw-Hill, New York, Chap 324, pp 1798-1811
93. McPhaul MJ, Marcelli M, Tilley WD, Griffin JE, Wilson JD 1991 Androgen resistance caused by mutations in the androgen receptor gene. FASEB J 5:2910-2915
94. Griffin JE, Wilson JD 1992 Disorders of the testes and the male reproductive t ract. In: Wilson JD, Foster DW (eds), Williams Textbook of Endocrinolgy, 8th Edition, WB Saunders, Philadelphia, pp 799-852
95. Carr BR, Griffin JE 1992 Fertility control and its complications. In: Wilson JD, Foster DW (eds), Williams Textbook of Endocrinology, 8th Edition, WB Saunders, Philadelphia, pp 1007-1031
96. Griffin JE 1992 Dynamic tests of endocrine function. In: Wilson JD, Foster DW (eds), Williams Textbook of Endocrinology, 8th Edition, WB Saunders, Philadelphia, pp 1663-1670
97. Griffin JE 1992 Androgen resistance - the clinical and molecular spectrum. N Engl J Med 326:611-618
98. Zoppi S, Marcelli M, Deslypere J-P, Griffin JE, Wilson JD, McPhaul MJ 1992 Amino acid substitutions in the DNA-binding domain of the human androgen receptor are a frequent cause of receptor-binding positive androgen resistance. Mol Endocrinol 6:409-415
99. Griffin JE, Wilson JD 1992 Disorders of sexual differentiation. In: Walsh PC, Retik AB, Stamey TA, Vaughan ED Jr (eds), Campbell's Urology, 7th Editiion, WB Saunders, Philadelphia, pp 1509-1542
100. Marcelli M, Tilley WD, Zoppi S, Griffin JE, Wilson JD, McPhaul MJ 1992 Molecular basis of androgen resistance. J Endocrinol Invest 15:149-159
101. Thigpen AE, Davis DL, Milatovich A, Mendonca BB, Imperato-McGinley J, Griffin JE, Francke U, Wilson JD, Russell DW 1992 Molecular genetics of steroid 5 -reductase 2 deficiency. J Clin Invest 90:799-809
102. McPhaul MJ, Marcelli M, Zoppi S, Wilson CM, Griffin JE, Wilson JD 1992 Mutations in the ligand-binding domain of the androgen receptor gene cluster in two regions of the gene. J Clin Invest 90:2097-2101
103. Warner CL, Griffin JE, Wilson JD, Jacobs LD, Murray KR, Fischbeck KH, Dickoff D, Griggs RC 1992 X-linked spinomuscular atrophy: A kindred with associated abnormal androgen receptor binding. Neurology 42:2181-2184
104. Wilson CM, Griffin JE, Wilson JD, Marcelli M, Zoppi S, McPhaul MJ 1992 Immunoreactive androgen receptor expression in patients with androgen resistance. J Clin Endocrinol Metab 75:1474-1478
105. McPhaul MJ, Marcelli M, Zoppi S, Griffin JE, Wilson JD 1993 The spectrum of mutations in the androgen receptor gene that cause androgen resistance. J Clin Endocrinol Metab 76:17-23
106. Zoppi S, Wilson CM, Harbison MD, Griffin JE, Wilson JD, McPhaul MJ, Marcelli M 1993 Complete testicular feminization caused by an amino terminal truncation of the androgen receptor with downstream initiation. J Clin Invest 91:1105-1112
107. Griffin JE 1993 The physiology of the testis and male reproductive tract and disorders of testicular function. In: Carr BR, Blackwell RE (eds), Textbook of Reproductive Medicine, Appleton & Lange, Norwalk, CT, Chap 13, pp 221-245
108. Griffin JE 1993 The male menopause. In: Wilson JD, Braunwald E, Isselbacher KJ, Martin JB, Fauci AS, Kasper DL (eds), Harrison's Principles of Internal Medicine, Supplement 6, McGraw-Hill, New York, pp 3-14
109. Jockenhovel F, Rutgers JKL, Mason JS, Griffin JE, Swerdloff RS. 1993 Leydig cell neoplasia in a patient with Reifenstein syndrome. Experimental and Clin Endocrinol 101:365-370
110. Wilson JD, Griffin JE, Russell DW 1993 Steroid 5 -reductase 2 deficiency. Endocr Rev 14:577-593
111. Griffin JE, Wilson JD 1994 Disorders of the testes. In: Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL (eds), Harrison's Principles of Internal Medicine, 13th Edition, McGraw-Hill, New York, Chapter 339, pp 2006-2017
112. Wilson JD, Griffin JE 1994 Disorders of sexual differentiation. In: Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL (eds), Harrison's Principles of Internal Medicine, 13th Edition, McGraw-Hill, New York, Chapter 342, pp 2039-2051
113. Wilson JD, Griffin JE, Russell DW 1994 Steroid 5 -reductase 2 deficiency: the molecular and clinical spectrum. In: Dufau ML, Fabbri A, Isidori A, (eds), Cell and Molecular Biology of the Testis, Frontiers in Endocrinology, Vol 5. Ares- Serono Symposia Series, Rome, pp. 17-26
114. Griffin JE, Wilson JD 1994 The testis. In: Besser GM, Thorner MO (eds), Clinical Endocrinology, 2nd Edition, Mosby-Wolfe, London, Chapter 11, pp 11.1-11.26.
115. Marcelli M, Zoppi S, Wilson CM, Griffin JE, McPhaul MJ. 1994 Amino acid substitutions in the hormone-binding domain of the human androgen receptor alter the stability of the hormone receptor complex. J Clin Invest 94:1642-1650
116. Griffin JE, McPhaul MJ, Russell DW, Wilson JD. 1995 The androgen resistance syndromes: Steroid 5 -reductase 2 deficiency, testicular feminization, and related disorders. In: Scriver CR, Beaudet AL, Sly WS, and Valle D (eds), The Metabolic and Molecular Bases of Inherited Disease, 7th Edition, McGraw-Hill, New York, Vol. II, Chap. 95, pp 2967-2998
117. Laue L, WU SM, Kudo M, Hsueh AJW, Cutler Jr., GB, Griffin JE, Wilson JD, Brian C, Berry AC, Grant DB, Chan W.Y 1995 A nonsense mutation of the human luteinizing hormone receptor gene in Leydig cell hypoplasia. Hum Mol Genet 4:1429-1433
118. Allèra A, Herbst MA, Griffin JE, Wilson JD, Schweikert H-U, McPhaul MJ. 1995 Mutations of the androgen receptor coding sequence are infrequent in patients with isolated hypospadias. J Clin Endocrinol Metab 80:2697-2699
119. Griffin JE, Wilson JD, McPhaul MJ 1995 The clinical and molecular spectrum of disorders of the androgen receptor. In: Hedon B, Bringer J, and Mares P (eds), A Current Overview in the Proceedings of the 15th World Congress on Fertility and Sterility, Montpellier, France, September 17-22 The Parthenon Publishing Group, New York, Chap 37, pp 279-281
120. Andersson S, Geissler WM, Wu L, Davis DL, Grumbach MM, New MI, Schwarz HP, Blethen SL, Mendonca BB, Bloise W, Witchel, SF, Cutler GB Jr., Griffin JE, Wilson JD, Russell DW 1996 Molecular Genetics and Pathophysiology of 17 - Hydroxysteroid dehydrogenase 3 deficiency. J Clin Endocrinol Metab 81:130-136
121. Wilson JD, Griffin JE, Russell DW 1996 Steroid 5 -reductase: one disorder/two enzymes/many unsolved problems. In: Bhasin S, Gabelnick HL, Spieler JM, Swerdloff RS, Wang C, Kelly C (eds) Pharmacology, Biology, and Clinical Applications of Androgens. Current Status and Future Prospects, Wiley-Liss, New York, pp 57-63
122. Griffin JE.1996 Male infertility. Diagnostic Endocrinology and Metabolism 14(5) 127-34
123. Wilson JD, Griffin JE, McPhaul MJ 1996 Genetic defects in the androgen receptor: phenotypic differences can result from several mechanisms. Frontiers of Endocrinology. 16: 91-98
124. Griffin JE, Wilson JD 1997 clinical manifestations and pathogenesis of disorders of the androgen receptor. In: Flier JS, Snyder PJ (eds) UpToDate in Endocrinology and Diabetes, Vol. 5, pp 1-8
125. Griffin JE, Wilson JD 1997 Diagnosis and treatment of disorders of the androgen receptor. In: Flier JS, Snyder PJ (eds) UpToDate in Endocrinology and Diabetes, Vol. 5, pp 1-8
126. Griffin JE, Wilson JD 1997 Steroid 5 -reductase 2 deficiency. In: Flier JS, Snyder PJ (eds) UpToDate in Endocrinology and Diabetes, Vol. 5, pp 1-6
127. Griffin JE, Wilson JD 1997 Male reproductive physiology. In: Flier JS, Snyder PJ (eds) UpToDate in Endocrinology and Diabetes, Vol. 5, pp 1-9
128. Griffin JE, Wilson JD 1997 Normal male sexual differentiation. In: Flier JS, Snyder PJ (eds) UpToDate in Endocrinology and Diabetes, Vol. 5, pp 1-3
129. Griffin JE, Wilson, JD 1998 Disorders of the testes. In: Wilson JD, Braunwald E, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Kasper DL, Hauser SL, Longo DI (eds), Harrison's Principles of Internal Medicine, 14th Edition, McGraw-Hill, New York, Chap 336, pp 2087-2097
130. Wilson JD, Griffin, JE 1998 Disorders of sexual differentiation. In: Wilson JD, Braunwald E, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Kasper DL, Hauser SL, Longo DI (eds), Harrison's Principles of Internal Medicine, 14th Edition, McGraw-Hill, New York, Chap 339, pp 2119-2131
131. Griffin JE, Wilson JD 1998 Disorders of the testes and the male reproductive tract. In: Wilson JD, Foster DW, Kronenberg HM, Larsen PR(eds), Textbook of Endocrinolgy, 9th Edition, WB Saunders, Philadelphia, pp 819-876
132. Carr BR, Griffin JE, Wilson JD 1998 Fertility control and its complications. In: Foster DW, Kronenberg HM, Larsen PR (eds), Williams Textbook of Endocrinology, 9th Edition, WB Saunders, Philadelphia, pp 901-926
133. Berry AC , Brain C, Chan W, Cutler GB, Grant DB, Griffin JE, Hallermeier KM, Laue L, Wu S 1998 Inactivation of the luteinizing hormone/chorionic gonadotropin receptor by an insertional mutation in leydig cell hypoplasia. Mol Endocrinol. 12: 1651-1660
BOOKS
1. Griffin JE. Manual of Clinical Endocrinology and Metabolism. McGraw-Hill, New York, 1982
2. Griffin JE, Ojeda SR (eds). Textbook of Endocrine Physiology. Oxford University Press,New York, 1988
3. Griffin JE, Ojeda SR (eds). Textbook of Endocrine Physiology, 2nd Edition, Oxford University Press, New York, 1992
4. Griffin JE, Ojeda SR (eds). Textbook of Endocrine Physiology, 3rd Edition, Oxford University Press, New York, 1996