Robert Toto, M.D.
Professor of Medicine
Division of Nephrology

Several distinct studies are ongoing in and in association with my group.

Robert Toto, M.D.
African-American Study of Kidney Disease and Hypertension Cohort Study
This project involves the factors that determine progression of kidney disease in those with hypertensive nephrosclerosis. It is a prospective cohort study that with a large and long-standing (10 years) database funded by NIH.

Robert Toto, M.D.
Co-mentor: Gloria Vega, Ph.D.
Improving Outcomes in Diabetic Nephropathy This is a double-blind randomized clinical trial designed to determine whether combinations of drugs that block the renin-angiotensin system are more protective than single agents in diabetics with nephropathy.

Robert Toto
Co-mentor: Susan Hedayati, M.D.
Vascular calcification and atherosclerosis in kidney disease This study is designed to investigate the factors involved in vascular calcification in the process of atherosclerosis in patients with early kidney disease. Sophisticated imaging techniques of the heart and vasculature are employed to evaluate this disease in the Dallas Heart Study.

Robert Toto, M.D.
Predicting Outcomes in Diabetic Nephropathy This project explores the potential of plasma and urine proteome to predict outcomes in diabetics with established renal disease. It is collaboration between clinical and basic science laboratories.