Education
Dr.
Cater attended medical school at the
University of Oklahoma College of
Medicine and completed his residency
in Internal Medicine at the George
Washington University Medical Center
in Washington, D.C. Following his
residency training, Dr. Cater joined
UT Southwestern as a Clinical Nutrition
Research Fellow in the Center for
Human Nutrition and a clinical fellow
in the Division of Endocrinology of
the Department of Internal Medicine.
After his fellowship, Dr. Cater joined
the faculty of the Department of Clinical
Nutrition as an Instructor. Later
he became a Clinical Nutrition Research
Scholar and transferred to the Department
of Internal Medicine.
Research Accomplishments
During
his fellowship training in the Center
for Human Nutrition Dr. Cater investigated
the effects of different forms of
saturated fatty acids on serum cholesterol
levels. He made the important observation
that an medium-chain length fatty
acids (C8:0 and C10:) raise the serum
LDL cholesterol level. This finding
was contrary to earlier impressions
that medium-chain, saturated fatty
acids do no increase LDL cholesterol.
The finding is important because it
rules out the possibility that medium-chain
saturates can replace other saturated
fatty acids in diets designed to lower
LDL-cholesterol levels. After
Dr. Cater became a Clinical Nutrition
Research Scholar his attention turned
to the exiting new area of plant stanols.
The latter are derivatives of sitosterol
and have been shown to reduce serum
LDL-cholesterol levels by inhibiting
the absorption of cholesterol. Dr.
Cater has obtained grants to study
the effects of plant stanols in several
different types of patients. He also
had played a major role in professional
education of the potential utility
of plant stanols as dietary adjuncts
for LDL reduction. He further participated
in an important study showing how
plant stanols can augment the cholesterol-lowering
of dietary therapy in patients receiving
statin therapy. Dr. Cater has
emerged as an authority on the role
of plant stanols for the treatment
of elevated LDL cholesterol.
In addition, Dr. Cater participates
in all of the clinical research projects
being carried out in the VA Medical
Center. These projects include a variety
of studies on pharmacological agents
affecting serum lipid disorders. Dr.
Cater further is a national spokesman
for the Center for Human Nutrition
in several areas of nutrition, particularly
in the areas of functional foods and
nutraceuticals. Dr.
Cater's research focuses on the dietary
and pharmacological management of
dyslipidemia. He conducts metabolic
ward feeding studies and outpatient
diet and drug studies. He also participates
in multicenter diet and drug trials.
Dr. Cater is particularly interested
in the role of dietary adjuncts, such
as functional foods and nutraceuticals,
in the management of moderate hypercholesterolemia
and in their potential utility in
augmenting the cholesterol-lowering
effect of diet in patients already
on statin therapy. The models for
this are foods fortified with plant
stanol ester. Dr. Cater is active
on both the national and international
levels in further investigating the
role of plant stanol ester in both
the clinical and public health approaches
to controlling cholesterol levels.
Professional
Societies, Awards, and Achievements
Dr. Cater
is a member of the American Medical
Association.