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Scott M. Grundy, MD, PhD

UT Southwestern Appointment

Scott M. Grundy, M.D., Ph.D. is the director of the Center for Human Nutrition Chairman of the Department of Clinical Nutrition at
UT Southwestern and chief of the metabolic unit, Veterans Affairs Medical Center, in Dallas, Texas. He is Distinguished Professor of Internal Medicine at UT Southwestern.


Previous Appointments

Previously, Dr. Grundy had been a Professor of Medicine at the University of California, San Diego and Chief of the Metabolic Division at the San Diego VA Medical Center. Before that, he was director of the National Institutes of Health Phoenix Clinical Research Unit, and Assistant Professor at Rockefeller University, New York City, and Baylor College of Medicine, Houston, Texas.

Education

Dr. Grundy received his B.S. at Texas Tech College, Lubbock Texas, MD and MS at Baylor College of Medicine, Houston, and Ph.D. at Rockefeller University, New York City. He did residency training in Internal Medicine at Baylor College of Medicine and at New York Hospital, New York City.

Research Accomplishments

Dr. Grundy's major research area is in cholesterol and lipoprotein metabolism. He has published over 300 original papers, and numerous solicited articles and chapters. Notable research accomplishments include the development of methods for measuring cholesterol balance and biliary lipid secretion in humans, identifying the metabolic causes of cholesterol gallstones, defining effects of saturated and unsaturated fats, especially monounsaturated fatty acids, on cholesterol and lipoprotein metabolism, uncovering genetic defects underlying hypercholesterolemia and other forms of dyslipidemia, identifying metabolic defects in hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia, and defining mechanisms of action of several lipid-lowering drugs, notably fibrates and HMG CoA reductase inhibitors (statins).

Role in the Center for Human Nutrition

Dr. Grundy has played significant roles in development of public policy on the prevention of cardiovascular disease. This work has been carried out through the American Heart Association, the National Cholesterol Education Program, the National Academies Institute of Medicine, and the U.S. Government. He has been chair of a number committees of the American Heart Association were he has assisted in the development of position statements on nutrition, treatment of hyperlipidemia, primary prevention and secondary prevention of coronary heart disease, risk assessment, and diabetes and cardiovascular disease. Dr. Grundy is the American Heart Association's representative to the US National Cholesterol Education Program (NCEP). In this role he has assisted in the development of "cholesterol policy" including three reports of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults; in the second report he was chair of the panel, and he also is chair of the panel that is producing the third report. He also was a member of the NCEP panel that produced public health guidelines. He served on the committee that wrote the Dietary Guidelines for Americans 2000. In the Institute of Medicine, he has served on the Food and Nutrition Board (FNB); and he is a member of the standing FNB committee on Dietary Reference Intakes (DRI); and he currently is a member of the panel developing DRIs for macronutrients.

Professional Societies, Awards and Achievements

Dr. Grundy is a member of the American Society for Clinical Investigation, the American Association of Physicians, and the National Academies Institutes of Medicine. He received The Merit Award from The American Heart Association in 1983. He gave the Lydia J. Roberts Memorial Lecture in Chicago in 1988 and the American Heart Association's George Lyman Duff Lecture in 1990. In 1990, he was awarded an honorary degree in medicine from the University of Helsinki, Finland. In 1994, he received the Roger J. Williams Award in Preventive Nutrition. He was made a member of the Institute of Medicine in 1996, in 1997 he received the Bristol Myers Squibb Award for Distinguished Achievement in Nutrition Research, and in 1998, the American Society for Clinical Nutrition's E.V. McCollum award. In 2000, he became President Elect of the International Atherosclerosis Society.

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Last updated: September 25, 2003
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